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A novel stable [7]helicene with partial biradical character

A novel stable [7]helicene with partial biradical character

Helicenes, a class of polycyclic aromatic compounds consisting of nonplanar ortho-fused aromatic rings, have attracted significant research attention owing to their unique structural and physical properties and their significance in fundamental science, as revealed in recent studies. A helicene with an open-shell biradical ground state would be able to participate in a variety of kinds of chemistry. In this state, one of the π bonds is taken to the limit of dissociation, and two weakly coup...

Long-term observations reveal variability of the Kuroshio east of Taiwan

Long-term observations reveal variability of the Kuroshio east of Taiwan

Currents act as rivers in the sea. Like a giant river in the western Pacific Ocean, Kuroshio is the western boundary current of the North Pacific subtropical gyre, and it originates from the northern branch of the North Equatorial Current (NEC) bifurcation off the east coast of the Philippines. The Kuroshio links the Asian marginal seas by flowing northward to the east of Luzon Island, by the Luzon Strait, east of Taiwan, along the continental slope of the East China Sea, and along the south coa...

Fluctuating interaction network and time-varying stability of a natural fish community

Fluctuating interaction network and time-varying stability of a natural fish community

Understanding the mechanisms underlying community stability is key to ecosystem conservation and management, as a fluctuating (less stable) community is vulnerable to catastrophic shifts. Theoretical studies have indicated that multispecies interactions play a critical role in determining the stability of the community. For example, species diversity, the topology of the interaction network, the distribution of interaction strengths, and the composition of interaction types can affect community ...

Confocal pump-probe backscattering microscopy for investigating single nanomaterials

Confocal pump-probe backscattering microscopy for investigating single nanomaterials

In recent decades, ultrafast optical spectroscopy has provided a fundamental understanding of carrier dynamics (such as electrons and phonons) in many emergent materials, such as nanomaterials and 2D materials. Nevertheless, these materials typically possess spatial inhomogeneity, and it is therefore highly desirable to integrate ultrafast spectroscopy and optical microscopy to provide full spatiotemporal characterization of nanosized features. Here, we demonstrated a novel confocal pump-probe m...

Blue light regulates hair regrowth via the eye

Blue light regulates hair regrowth via the eye

Prof. Sung-Jan Lin (林頌然) from the Institute of Biomedical Engineering and Assoc. Prof. Shih-Kuo Chen (陳示國) from the Department of Life Sciences have published a paper discussing the transmission of external sudden intense light through the intrinsically photosensitive retinal ganglion cell (ipRGC). The suprachiasmatic nucleus (SCN) further stimulates the sympathetic nerves to activate hair follicle stem cells. Stem cells are regulated by the local microenvironment and the systemic environment to...

Ruminococcus gnavus heralds the onset of infantile allergic diseases: a twin cohort study

Ruminococcus gnavus heralds the onset of infantile allergic diseases: a twin cohort study

The World Health Organization has predicted that the prevalence of bronchial asthma will increase globally in forthcoming years. Early life gut microbial dysbiosis is currently recognized as a key determinant of immune dysregulation, which is associated with a broad spectrum of allergic disorders. However, we still do not know what or how gut microbe(s) are responsible for allergy establishment. It is arguable that early and rapid colonization by Clostridium/Bacteroides/Escherichia coli a...

Pioneer studies on opinion mining and sentiment analysis

Pioneer studies on opinion mining and sentiment analysis

Opinion mining and sentiment analysisOpinion mining and sentiment analysis, a practical application of natural language processing (NLP), has attracted attention for more than a decade because a large amount of opinionated information is generated and disseminated across various platforms on the internet. On the one hand, people are willing to share their feelings and thoughts. On the other hand, people often refer to majority opinions before making decisions. The Natural Language Processing Lab...

System for automatic ICD-10 classification from free-text medical data

System for automatic ICD-10 classification from free-text medical data

Our study aimed to construct a system for ICD-10 coding systems produced by supervised machine learning techniques to categorize automatically free-text medical data using solely their content. We used numerous machine learning techniques, such as supervised machine learning approaches. At present, disease classification relies heavily on human labor to read a large amount of written material, such as discharge diagnoses, chief complaints, medical histories, and operation records, as the basis f...

Artificial, augmented, and human intelligence for medical image analysis for our health

Artificial, augmented, and human intelligence for medical image analysis for our health

We all aspire to be healthy. Can artificial intelligence (AI) help us in our quest?Thanks to ubiquitously available datasets, fast-growing computing power, and the latest innovative algorithms, AI continues to surprise us by changing the world at a rapid pace. AI unmanned vehicles have been around for some time. The FDA approved the first AI-powered diabetic retinopathy diagnostic device that does not require a doctor's supervision in April 2018. Google recently claimed that its AI voice technol...

AttriRank: the state-of-the-art model for unsupervised ranking

AttriRank: the state-of-the-art model for unsupervised ranking

Node ranking in a graph is an important technique underlying many real-world applications. Take web search for example. This task is essential for returning important (or highly ranked) websites that are relevant to a query. Because the entire Internet with all of its webpages and hyperlinks forms a graph, a technique that ranks nodes in a graph becomes essential for this application. Such a ranking technique would also be useful in identifying influential persons or opinion leaders in a large s...