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The barriers and challenges of urban climate governance in Taiwan: a multilevel governance perspective

The barriers and challenges of urban climate governance in Taiwan: a multilevel governance perspective

The role of cities in climate governance Urban climate governance has become a vital aspect of contemporary global governance. In 1976, when the United Nations held the first UN-Habitat in Vancouver, Canada, two-thirds of the world population was concentrated in rural areas. Now, forty years later, half of the world population lives in cities, and fast-paced urbanization has created grand challenges for urban governance systems. Since the industrial revolution, developing economic and social ...

Introduction to Climate Change Governance and Law

Introduction to Climate Change Governance and Law

From the Kyoto Protocol to the Paris Agreement: Climate Change 2.0 The year 2016 saw two surprising events in the world of climate change governance. First, the Paris Agreement was ratified by more than 55 state parties, which together account for more than 55% of the world’s greenhouse gas emissions, on October 5, and it officially became effective on November 4. Second, Donald Trump, a climate change skeptic, was elected as President of the United States, one of the largest greenhouse gas-e...

The genetic mystery behind lung cancer

The genetic mystery behind lung cancer

A YAP1 mutation is a germline risk allele for lung adenocarcinoma According to statistics from the Ministry of Health and Welfare in Taiwan, lung cancer is the leading cause of death among malignancies. In non-smokers, lung adenocarcinoma is the predominant histologic type. However, early diagnosis of lung adenocarcinoma is difficult because there are no obvious symptoms and no history of smoking. Because early symptoms of lung adenocarcinoma are vague, genetic factors may be useful for ...

The mechanism stopping DNA replication inspires cancer research

The mechanism stopping DNA replication inspires cancer research

NTU discovers how cell stabilizes its division through terminating telomere replication, inspires cancer research The National Taiwan University research team, which is led by Prof. Shu-Chun Teng from the Department of Microbiology, College of Medicine, has discovered a mechanism related to DNA replication and cellular stability. This discovery is very likely to have crucial implications for cancer research and treatment because understanding this mechanism might allow scientists to prevent...

Invasion--Unraveling the mechanism underlying invasive yeast growth

Invasion--Unraveling the mechanism underlying invasive yeast growth

In energy-depleted environments, cells are stimulated to migrate toward nutritional or carbonic sources and, in some cases, may even become invasive. Why is this so? Many fungi will switch to filamentous growth to search for nutrients in energy-depleted environments. Filamentous growth is considered invasive and is associated with Arf3p activation in yeast, which is the homolog of mammalian Arf6. ADP-ribosylation factors (Arfs) are small GTP-binding proteins that can hydrolyze GTP and...

Systems biology of the autophagy regulatory mechanisms

Systems biology of the autophagy regulatory mechanisms

Autophagy, as a conserved pathway in eukaryotic cells, plays a critical role in maintaining cellular homeostasis by delivering cytoplasmic materials to lysosomes/vacuoles for degradation. Abnormal autophagy activities are associated with several human diseases, such as diabetes, neurodegenerative diseases, and cancers. Aging process is found accelerated by compromised autophagy functions in many model organisms, including worms and plants. All these observation leads to the possibilities of mani...

Aging is a complicated cellular process that regulatory genes gradually lose their functions. Current knowledge about aging is related to telomere shortening induced checkpoint activation and mutagene

Aging is a complicated cellular process that regulatory genes gradually lose their functions. Current knowledge about aging is related to telomere shortening induced checkpoint activation and mutagene

Aging is a complicated cellular process that regulatory genes gradually lose their functions. Current knowledge about aging is related to telomere shortening induced checkpoint activation and mutagenesis, free radicals-mediated chemical damages, mitochondria defect-mediated damage, DNA damage and mutagenesis during DNA repair. Studies provided evidence that calorie restriction reduces the risk of aging-related diseases, including cancer, diabetes and cardiovascular diseases, etc, and also ex...

Establishment of a minimal disease miniature pig production system for biochemical research

Establishment of a minimal disease miniature pig production system for biochemical research

The present study is aimed to use Lee-Sung strain minipig as an animal model for biomedicine research pertinent to disease mechanism model and pharmaceutical drugs screening platform. The second part is: 1. including the sustainable use of microsatellite genetic markers to monitoring genetic variation of Lee-Sung strain minipig population and the establishment of pedigree data. Microsatellite markers are useful tools in assessing genetic diversity of populations. In this study, seven microsatell...

Novel Low Band-Gap Polymer/Nanomaterial Hybrid Solar Cells; A Leaping Advance toward 10-15% Power Conversion Efficiency

Novel Low Band-Gap Polymer/Nanomaterial Hybrid Solar Cells; A Leaping Advance toward 10-15% Power Conversion Efficiency

First of all, a good news to be shared is regarding our seminal studies on the quinoxaline-based solar enery cell, which has been published in Chem. Mater. (Chem. Mater. 2012, 24, 4766–4772). This paper has been categorized as a highly cited paper and its number of citation was recently over double digits (> 100). This paper dealt with syntehses of a new fluorinated quinoxaline-based polymer and its thus prepared solar cell that achived high device performance with a photon conversion efficiency...

Dean Lee exchanged research-enhancing approaches with SACI Deputy Director Prof. Satoshi ABE

Dean Lee exchanged research-enhancing approaches with SACI Deputy Director Prof. Satoshi ABE

Dean Fang-Jen Lee paid a return visit to Kyoto University 1-2 September 2014 to strengthen ties with KU counterparts and seek opportunity for collaboration.