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Molecular Genetics of Chronic Lymphocytic Leukemia in Taiwan: Clinical and Pathogenetic Implications

Molecular Genetics of Chronic Lymphocytic Leukemia in Taiwan: Clinical and Pathogenetic Implications

Chronic lymphocytic leukemia (CLL) is the most prevalent adult leukemia in the Western world. CLL belongs to the indolent lymphoma category, but its clinical course varies widely. During the preceding three decades, many clinical and molecular features have been identified as predictors of outcome or of response to therapy. These molecular and clinical markers of CLL have greatly improved our understanding of the biology of this disease and contributed to the optimization of individual patients&...

Self-assembly of conjugated rod-coil block copolymers for organic electronics

Self-assembly of conjugated rod-coil block copolymers for organic electronics

The field of organic electronics has enjoyed increasing interest over the past decade. Organic light-emitting diodes, field-effect transistors and solar cells have a promising future, with some products already commercially available. Polymers typically offer good solution processability, paving the way for potential low-cost and large-area applications. However, the morphology always plays the decisive role in such devices since it has a large effect on the charge-transport properties.Block cop...

High-performance CsPb1-xSnxBr3 perovskite quantum dots for  highly efficient light-emitting diodes

High-performance CsPb1-xSnxBr3 perovskite quantum dots for highly efficient light-emitting diodes

All inorganic CsPbBr3 perovskite quantum dots (QDs) have attracted considerable interest because of their high photoluminescence, tunable and narrow emission wavelength, and facile synthesis. Given these advantages, all inorganic CsPbBr3 perovskite QDs can be used in solar cells, lasing, light-emitting diodes (LEDs) and bioimaging. However, the toxicity of Pb2+ has a negative impact on the environment. Hence, the total or partial replacement of Pb2+ is necessary. At present, the most suitable su...

Deciphering brown root rot disease of trees

Deciphering brown root rot disease of trees

The comparative and population genomics landscape of Phellinus noxius Under most circumstances, fungi coexist with trees or act as saprotrophs responsible for carbon and nitrogen cycling in forest systems. The order Hymenochaetales is dominated by wood decay fungi and belongs to Agaricomycetes in Basidiomycota. Most species in this order are saprotrophic or weakly pathogenic, but a few of these species exhibit strong pathogenicity. In various parts of the world, there has been an emergence of...

Positive in-plane magnetoresistance induced by nanodomain boundaries in graphene

Positive in-plane magnetoresistance induced by nanodomain boundaries in graphene

Graphene supports long spin lifetimes and long diffusion lengths, making it promising for spintronics. However, rendering graphene magnetic remains a fundamental challenge. Among the different types of graphene, graphene with zig-zag edges and ripples are the most promising candidates, as zig-zag edges are predicted to host spin-polarized electronic states and ripples can induce spin–orbit coupling (SOC). We investigated the magnetoresistance (MR) of graphene grown on SiC/Si(001) wafers, i...

Evidence-based international recommendations for difficult biliary access

Evidence-based international recommendations for difficult biliary access

Amust-read for endoscopistsEndoscopic retrograde cholangiopancreatography (ERCP) is the preferred treatment for bile duct stones and plays an important role in the management of various diseases of the bile duct and pancreas. The first step in ERCP is advancement of the endoscope to the bile duct opening in the duodenum followed by entry into the bile duct; further endoscopic therapy is then administered. Difficulty achieving biliary access is a commonly encountered challenge, with an estimated ...

Strategies for improving the functionality of zeolitic imidazolate frameworks

Strategies for improving the functionality of zeolitic imidazolate frameworks

Tailoring nanoarchitectures for functional applicationsZeolitic imidazole frameworks (ZIFs), a subclass of metal-organic frameworks (MOFs) built with tetrahedral metal ions and imidazolates, offer permanent porosity and high thermal and chemical stability. While ZIFs possess some attractive physical and chemical properties, it remains important to enhance their functionality for practical applications. Here, we provide an overview of the extensive strategies that have been developed to imp...

Systematically selecting conservation areas for habitat quality and multiple ecosystem services protection

Systematically selecting conservation areas for habitat quality and multiple ecosystem services protection

Conservation areas generally consist of natural resources that must be sustained and preserved, such as habitats, species, ecosystems, and the services they provide. Accordingly, the natural environment of the conservation area is preserved and protected by policies that restrict certain human activities. Many academic studies have focused on the provisioning capacity of natural resources, but the importance and provisioning capacity of ecosystem services have often been neglected. Along with...

Bridging a way to their origins – Introduction to the NTU-USYD Collaborative Project

Bridging a way to their origins – Introduction to the NTU-USYD Collaborative Project

Interview:Professor Yu-Wen Chen Intercountry adoptions have been justified as being in the best interests of children who cannot receive suitable care in their country of origin. However, the rights and wellbeing of these children are a point of concern. Australia and Taiwan are indelibly linked by the adoption of Taiwanese-born children by Australian families through intercountry adoption. From 2011 to 2014, Taiwan sent the most infants to Australia and was the leading sending country for Au...

Historical Narratives in the Pre-Qin and Han Periods

Historical Narratives in the Pre-Qin and Han Periods

The long history of Chinese historical narratives that originated in the Shang-Zhou (商周) era, bloomed in the Warring States (戰國) period and prospered in the Han (漢) dynasty generated the greatest amount of narrative literature in the world. This book explores and discusses the pre-Qin (先秦) and Han historical narratives through Confucian classics and their commentaries, Chinese philosophy, Chinese historiography, and unearthed documents.The research methodology focuses on Zuo Zhuan and Guoyu with...