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Why should a guidebook, not a textbook, be written on Xunzi studies?

Why should a guidebook, not a textbook, be written on Xunzi studies?

This volume is neither an introduction to Xunzi’s (ca. 315-235 BCE) philosophy nor a collection of those research articles and essays that the author has conducted on the topic. It is instead a guidebook to “Xunzi Studies” and the research on Xunzi’s philosophy. I wrote this book mainly for those who conduct scholarly research about Xunzi or for those who must address his philosophy to discuss more popular thinkers such as Mencius (ca. 390-310 BCE) and Zhuangzi (?-?, late...

Climate Change and Societal Risk

Climate Change and Societal Risk

An Introduction to Sociology of Climate Change In modern society, nation states have faced various challenges, including housing bubbles, pollution, and unemployment, due to economic, environmental, and social risks. Generally, the modern state promotes technology to resolve social problems (e.g., promoting genetically modified organisms (GMOs) to secure food supplies) and thus justifies its legitimacy (Chou, 2014). The state seeks to secure basic human rights via technology and economic prog...

‘Micro’ organism, ‘Macro’ problems

‘Micro’ organism, ‘Macro’ problems

Studies of the MERS-CoV macro domain conducted by NTU structural biologists reveal a promising new therapeutic target. The macro domain is a well-known protein module with an affinity for ADP-ribose. RNA viruses such as severe acute respiratory syndrome (SARS)-CoV and Middle East respiratory syndrome (MERS)-CoV encode macro domains in their genomes, and the structures of several viral macro domains have been reported. However, the critical piece of the puzzle for the molecular structure and...

Quadruplex formation enhanced  by DNA methylation

Quadruplex formation enhanced by DNA methylation

It is well known that DNA secondary structure and methylation are involved in regulating gene expression in mammals. Research has shown that G-quadruplex (G4) structures, which are among the most prevalent non-B DNA structures, are key players in the control of gene transcription and regulation. Methylation of cytosine in CpG dinucleotides in promoter regions is a well-characterized epigenetic modification that plays an important role in regulating numerous cellular processes, including developm...

An integrative tool for phosphoproteomics: a key in systems biology

An integrative tool for phosphoproteomics: a key in systems biology

Systems biology is a data-driven science in which a combination of experimental and computational approaches are used to understand complex dynamic biological systems from a systems-wide perspective. Systems biology integrates various omics data, including genome, transcriptome, proteome and metabonome information, and explores the complex interactions among many levels of biological information to understand how these levels work together. Knowledge regarding interacting protein and signaling n...

Assembly of recombination-mediated DNA repair machinery

Assembly of recombination-mediated DNA repair machinery

How cells maintain their genome integrity is our long-term interest. The genome is constantly exposed to various endogenous and exogenous insults, ranging from endogenous replication stress to exogenous ultraviolet light and carcinogens. These insults cause a variety of DNA damage. DNA double-strand breaks (DSBs) are the most lethal chromosomal lesion if not repaired properly. DSBs trigger genomic instability and halt DNA replication. Cells have developed evolutionarily conservative mechanisms t...

Developmental changes in conceptual processing in children with autism

Developmental changes in conceptual processing in children with autism

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is characterized by deficits in social communication. To explore the developmental changes in communication deficits in ASD, a sample of children encompassing a wide age range, from childhood to adolescence, was recruited. Regarding neural substrates of language/communication in ASD, recent studies have shown aberrant neural activity during semantic processing. For example, there is reduced activation in the left inferior front...

Contextual modulation of to-be-remembered information in visual working memory

Contextual modulation of to-be-remembered information in visual working memory

Humans exhibit a remarkable cognitive flexibility to adapt to novel contexts. This great flexibility for new contexts relies on three cognitive abilities in concert. First, one must maintain goal-relevant representations in working memory (WM). Second, achieving one’s goal depends on the anticipation of upcoming events, and one must act in such a way that the future outcome will be in accordance with the desired outcome. Third, such anticipation relies on one’s past experiences assoc...

Deep-sea corals and coral-bioeroding foraminifera in the South China Sea

Deep-sea corals and coral-bioeroding foraminifera in the South China Sea

Coral reefs are shallow-water ecosystems that occur in tropical and subtropical seas. They feature very high biodiversity and primary productivity, as well as beautiful scenery. The species diversity and ecology of the coral reefs bordering Taiwan have been the focus of marine biology studies in the past several decades. However, the biodiversity of deep-sea corals in the seas surrounding Taiwan has not been investigated. From 2013 to 2016, we conducted field surveys on the species diversity and...

Deep-sea ecosystem functions linked to biodiversity over the past 20,000 years

Deep-sea ecosystem functions linked to biodiversity over the past 20,000 years

Biodiversity-ecosystem function (BEF) relationships have received much attention from ecologists, conservation biologists, and managers because they can be used to infer the consequences of losses of biodiversity on earth. Such losses are occurring rapidly due to biomass exploitation, habitat degradation, and especially global climate change. Since the mid-1990s, hundreds of experiments have manipulated the richness of plant or animal species or different combinations of functional groups in the...