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Facile self-assembly of metallo-supramolecular ring-in-ring and spider web structures using multivalent terpyridine ligands

Facile self-assembly of metallo-supramolecular ring-in-ring and spider web structures using multivalent terpyridine ligands

A research team led by Professor Yi-Tsu Chan in the Department of Chemistry at National Taiwan University aims to develop facile approaches to the assembly of predesigned building blocks into desired nanostructures via weak intermolecular interactions. Building on fundamental coordination and organic chemistry, they conduct systematic studies on how ligand geometry affects self-assembled structures in solution. Recently, it was found that a series of metallo-supramolecular ring-in-ring structure...

Mechanically interlocked daisy-chain-like structures as multidimensional molecular muscles

Mechanically interlocked daisy-chain-like structures as multidimensional molecular muscles

Daisy chains are garlands of flowers often worn as bracelets or necklaces (Figure 1). Because of their beautiful structures and possibly muscle-like motions, cyclic molecular daisy chains ([cn]DCs, where n is the number of repeating units) have long been attractive synthetic targets for supramolecular chemists. The significant entropic preference for small [c2]DCs has meant, however, that the selective assembly of higher-order homologues (n ≥ 3) remains highly challenging. Figure 1. A...

Spatially resolved imaging of photocarrier generation and band alignment at the perovskite/PbI2 heterointerfaces of perovskite solar cells by using light-modulated scanning tunneling microscopy

Spatially resolved imaging of photocarrier generation and band alignment at the perovskite/PbI2 heterointerfaces of perovskite solar cells by using light-modulated scanning tunneling microscopy

Organic-inorganic hybrid perovskite materials have recently shown remarkable power conversion efficiencies of up to 20% in photovoltaic applications. The inherent polycrystallinity of perovskite films is expected to significantly affect charge generation and transport efficiency under light illumination. Although it is known that an optimally thin PbI2 layer on perovskite crystals may enhance device performance, a detailed understanding of local electronic information regarding carrier generatio...

A novel porphyrin-containing polyimide for memory devices

A novel porphyrin-containing polyimide for memory devices

Since the first polymer-based electronic memory device was reported by Sliva et al., in 1970, these devices have attracted significant attention. Polymer-based electronic memory has been developed for various applications, including to establish next generation memory devices. Conventional memory devices based on semiconductor integrated circuits play an important role in the development of information technology. Compared with these inorganic memory devices, polymer-based memory devices have se...

Silicon carbide micro-ring all-optical processor

Silicon carbide micro-ring all-optical processor

Silicon (Si) photonics are able to overcome the transmission degradation induced by the limited RC time constraint in electronic integrated circuits via electro-optical switching or all-optical processing. Si photonic components, including light sources1, waveguides2-3, and photodiodes, have been developed to construct all-optical transmission platforms on a chip. When considering the optical processing, optical excitation or electrical injection can change the absorbance and refractive index or...

Hepatitis C viral infection increases the risk of lymphoid neoplasms

Hepatitis C viral infection increases the risk of lymphoid neoplasms

Chronic hepatitis C virus (HCV) infection is a global health problem, with an estimated 185 million chronic hepatitis C patients worldwide and approximately 0.7 million such patients in Taiwan. In addition to increased liver-related complications, such as cirrhosis and hepatocellular carcinoma, HCV infection is also associated with many extra-hepatic manifestations, including cardiovascular, renal, metabolic and central nervous system diseases. Previous epidemiological studies have suggested ...

Real-time in vivo 3D fluorescence sectioning microscopy

Real-time in vivo 3D fluorescence sectioning microscopy

Wide-field fluorescence microscopy is an imaging technique commonly used by researchers and clinicians for investigating rapid biological events occurring in live samples. However, standard wide-field microscopes lack the optical sectioning capabilities that would enable the capture of only in-focus information. Out-of-focus light and optical system aberrations lead to blurred images, limiting the use of conventional wide-field fluorescence microscopy in resolving volumetric biological samples. ...

Statins and the risk of pancreatic cancer in diabetic patients

Statins and the risk of pancreatic cancer in diabetic patients

Pancreatic cancer is the fourth leading cause of cancer deaths in the United States. Only approximately 15% to 20% of pancreatic cancer patients are diagnosed early enough to be eligible for surgery. The 1- and 5-year survival rates for all stages of pancreatic cancer combined are 20% and 6%, respectively. The low survival rate of patients with pancreatic cancer suggests a need for better treatment, early detection and improved chemoprevention strategies. Statins, which are inhibitors of 3-hydro...

Mediating analysis of the relationship between obesity and childhood asthma

Mediating analysis of the relationship between obesity and childhood asthma

Obesity and asthma are two significant public health problems with increasing prevalence during childhood. Prospective studies have suggested that obesity precedes the development of asthma. Several possible mechanisms have been postulated to explain this relationship, including an obesity-related reduction in lung volume, inflammatory mediators, obesity-related changes in hormone levels, and dyslipidemia. Based on our baseline Taiwan Children Health Study (TCHS) cohorts, we performed prospectiv...

The effects of pay-for-performance programs for diabetes care in Taiwan

The effects of pay-for-performance programs for diabetes care in Taiwan

Along with the economic growth and innovation in medicine, the increase in the number of patients with chronic conditions and multiple chronic conditions (MCCs) has become a challenge for health care systems worldwide. Diabetes mellitus is a chronic condition that is prevalent in Taiwan and many other industrialized nations. The clinical and economic consequences of diabetes, such as kidney dysfunction and dialysis, are burdensome. Taiwan implemented a single-payer National Health Insurance (...